N,N-Diethylethanolamine (DEAE)
The diethyl cousin of the N,N-dialkylethanolamine family: DEAE is the precursor to procaine, a steam-line corrosion inhibitor, and the feedstock for DEAE-cellulose — the workhorse resin behind countless chromatography purifications.
Chelora Chemicals supplies N,N-diethylethanolamine to pharmaceutical, power-plant chemical and specialty resin manufacturers worldwide, with full GHS documentation on every consignment.
Product identity
- CAS Number
- 100-37-8
- IUPAC name
- 2-(Diethylamino)ethan-1-ol
- Molecular formula
- C₆H₁₅NO
- Molecular weight
- 117.19 g/mol
- Boiling point
- 161.1 °C
- Melting point
- -70 °C
- UN Number
- UN 2686
- HS Code
- 2922 19*
* Confirm the current HS classification and import regulatory status for your destination with your own regulatory affairs team.
What N,N-Diethylethanolamine is used for
N,N-Diethylethanolamine (DEAE) is a colourless liquid with an ammoniacal, irritating odour, fully miscible with water. Both hydrogens on the amine nitrogen are replaced with ethyl groups, giving it a bulkier tertiary amine structure than its methylated cousin DMAE.
DEAE's best-known role is as a precursor in producing chemical commodities, including the local anaesthetic procaine, made by reacting it with 4-aminobenzoic acid. It is also used as a corrosion inhibitor in steam and condensate lines, where it neutralizes carbonic acid and scavenges oxygen, and as the precursor for DEAE-cellulose resin, used in ion exchange chromatography. Its solutions additionally absorb carbon dioxide.
Where it sits among the dialkylethanolamines
- N,N-Dimethylethanolamine two methyls — polyurethane/epoxy curing agent chemistry. See that page.
- N,N-Diethylethanolamine (this product) two ethyls — procaine precursor, steam-treatment and chromatography-resin chemistry.
- N-Methylethanolamine one methyl, secondary amine — intermediate and solvent chemistry. See that page.
Appearance and handling character
DEAE is both flammable and corrosive — harmful if swallowed, in contact with skin, or if inhaled, causes severe skin burns and eye damage, and may cause an allergic skin reaction — a combination that calls for ignition-source control alongside standard corrosive-liquid handling.
| Parameter | Typical value |
|---|---|
| Appearance | Colourless to pale yellow liquid |
| Assay | 98.5% min |
| Water content | 0.5% max |
| Colour (Hazen) | 15 max |
Important: the figures above are indicative of commercial material and are offered for planning only. The batch certificate of analysis is the governing document.
| Property | Value |
|---|---|
| Physical state | Colourless liquid; ammoniacal, irritating odour |
| Boiling point | 161.1 °C |
| Melting point | -70 °C |
| Density (20 °C) | 0.884 g/cm³ |
| Water solubility | Fully miscible |
| Amine class | Tertiary alkanolamine, no N–H |
Physical constants compiled from public reference data for CAS 100-37-8 and rounded for readability. Treat them as orientation, not as a specification.
Where our customers put this amine to work
One versatile tertiary amine, reaching from pharmaceutical synthesis to power-plant water treatment.
Procaine precursor
Reacted with 4-aminobenzoic acid to produce the local anaesthetic procaine.
- Pharmaceutical-intermediate grade
- Documented batch traceability
- Technical desk review on request
Steam/condensate corrosion inhibitor
Neutralizes carbonic acid and scavenges oxygen in steam and condensate lines.
- Technical grade specification
- Bulk & drum supply
- Contracted supply available
DEAE-cellulose feedstock
The precursor for DEAE-cellulose ion-exchange resin used in chromatography.
- Technical-grade specification
- Documented batch traceability
- Research and process-scale quantities
CO₂ absorption chemistry
Aqueous solutions absorb carbon dioxide, useful in gas-treating-adjacent applications.
- Technical grade specification
- Bulk tank or drum supply
- Retained sample held against the lot
General specialty chemical synthesis
A tertiary amine building block used across specialty chemical formulation.
- Packs from 25 kg drum / bulk
- Full analytical documentation available
- Technical desk review on request
Contract & scheduled supply
Pharmaceutical and power-plant chemical customers running continuous consumption are supported with scheduled bulk delivery.
- Annual contracts with scheduled call-off
- Price held across the contract period
- Second source held in reserve
How we supply N,N-Diethylethanolamine
Chelora Chemicals is a supplier and sourcing partner, not a manufacturer. DEAE's pharmaceutical-intermediate use case has very different documentation needs than its power-plant water-treatment use case — that shapes how we manage this line.
We place your order with whichever qualified producer best matches your required grade, your price point and your delivery window.
We keep a second qualified source on this line, so a single-plant disruption never becomes your production problem.
- Assay confirmed before we quote. Purity matters to both pharma-intermediate and steam-treatment performance.
- Flammable-liquid logistics managed end to end. Classification, labelling and carrier compliance confirmed before booking.
- UN 2686 documentation filed correctly. Every shipment carries the correct hazard declarations.
- Scheduled call-off scheduling. We hold contracted tonnage and release it against your consumption calendar.
- Batch traceability to the producing plant. Full chain of custody documentation on request.
- Export machinery handled in-house. Classification, approved packing, labelling, freight booking and customs paperwork are ours to manage.
Packed the way your plant receives it
Drum, IBC or bulk tank — tell us your preferred format and we will quote and classify to it.
200 L / 55 USG
Standard steel drums rated for flammable liquid storage and transport.
Intermediate bulk containers
For mid-volume orders where drum handling becomes a logistics burden.
Power-plant bulk volumes
Bulk liquid transport sized to continuous steam-treatment plant consumption.
Incoterms to suit you
Quoted on the Incoterm your purchasing team works to, with documentation filed before booking.
Trial / sample quantities
Small packs dispatched for process trials before a commercial order is placed.
Contracted call-off supply
We hold contracted tonnage and release it against your consumption calendar.
Flammable and corrosive — a dual hazard profile
DEAE's combination of flammability and corrosivity means both ignition control and skin/eye protection matter in routine handling. The summary below is orientation only — the safety data sheet supplied with your specific batch is the authoritative document.
Classified hazards
H226Flammable liquid and vapour.H302Harmful if swallowed.H312Harmful in contact with skin.H314Causes severe skin burns and eye damage.H317May cause an allergic skin reaction.H332Harmful if inhaled.
Always read the SDS issued with your specific batch. Eliminate ignition sources; handle with chemical-resistant gloves, splash goggles and adequate ventilation.
Storage
Store in tightly closed containers away from heat, sparks and open flame, in a well-ventilated area rated for flammable liquids.
Handling
Use with local exhaust ventilation and bond/ground equipment during transfer to control static discharge. Avoid skin and eye contact; have emergency eyewash and safety-shower provision nearby.
Transport
Shipped under UN 2686, Class 8 (corrosive, with flammability noted). We confirm and document packing group and exact classification for your specific shipment and destination.
Every batch, documented
We verify documentation before dispatch so there are no surprises at your incoming-goods bench.
Specification agreed
Assay confirmed against your pharmaceutical-intermediate or steam-treatment requirement before order placement.
Producer batch testing
The producing plant tests each batch against the agreed specification before release.
Documentation review
COA, SDS and transport paperwork checked by our desk before the shipment is booked.
Traceable dispatch
Each shipment is traceable to its producing batch, with full chain-of-custody records on request.
How N,N-diethylethanolamine is made
N,N-Diethylethanolamine is produced industrially by the reaction of ethylene oxide with diethylamine, a route that delivers the fully N,N-diethylated tertiary product directly, followed by purification and fractional distillation.
We do not publish operating process parameters here; this is background only. Full technical and safety documentation accompanies every shipment, and any process-specific detail you need is best confirmed directly with our technical desk.
| Chemical family | N,N-Dialkyl ethanolamine, tertiary |
|---|---|
| Basic character | Moderate base; tertiary amine, no N–H |
| Reactivity | Condenses with 4-aminobenzoic acid (procaine route); absorbs CO2 in solution |
| Related compound | N,N-Dimethylethanolamine (shorter N-alkyl groups) |
Explore the wider amine range
N,N-Diethylethanolamine, answered
What is N,N-diethylethanolamine (DEAE) used for?
What is DEAE-cellulose used for?
Is DEAE hazardous?
What grade do you supply?
What packing do you offer?
Do you manufacture this yourself?
- Need a related amine? See our N,N-Dimethylethanolamine and N-Methylethanolamine pages.
Get a quote on N,N-Diethylethanolamine today
Send us your required grade, pack size and delivery window. We will come back with a firm quote, lead time and full documentation.