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Dimethylformamide

DMF · CAS 68-12-2

A powerful polar aprotic solvent — behind acrylic and spandex fibre spinning, pharmaceutical synthesis, and specialty coatings.

Chelora Chemicals supplies dimethylformamide to fibre, pharmaceutical and specialty-chemical producers worldwide, with full documentation on every consignment.

  • Acrylic & spandex fibre spinning solvent
  • Pharmaceutical synthesis solvent
  • Polyurethane coatings solvent
  • Reproductive toxicant
  • Combustible liquid
  • UN 2265

Product identity

CAS Number
68-12-2
IUPAC name
N,N-Dimethylformamide
Molecular formula
C₃H₇NO
Molecular weight
73.09 g/mol
Boiling point
153 °C
Melting point
-61 °C
UN Number
UN 2265
HS Code
2924 19

Note: DMF is readily absorbed through skin, which is a major route of occupational exposure; confirm PPE requirements with your regulatory affairs team.

73.09g/mol molecular weight
153 °CBoiling point
0.944g/cm³ density
Fully miscibleWater solubility
Product overview

What DMF is used for

Dimethylformamide (DMF) is a colourless, high-boiling, polar aprotic liquid with a faint amine-like odour, fully miscible with water and most organic solvents. It is produced industrially by the reaction of dimethylamine with carbon monoxide (or, in some processes, with methyl formate).

DMF's largest use is as the spinning solvent for acrylic (polyacrylonitrile) and spandex (polyurethane) fibre, where its ability to dissolve these polymers at high concentration is essential to wet- and dry-spinning processes. It is also a workhorse solvent in pharmaceutical and agrochemical synthesis, in polyurethane and vinyl coating formulations, and as a reaction medium in specialty chemical manufacturing.

Where it sits in the petrochemical value chain

  • Dimethylamine + Carbon Monoxide the two feedstocks reacted into DMF (not separately listed on this site).
  • Dimethylformamide (this product) the aprotic solvent for the fibre, pharma and coatings applications below.
  • Acrylonitrile (Acrylic Fibre) a key downstream application as the acrylic-fibre spinning solvent. See Acrylonitrile.

Handling character

DMF is a suspected reproductive toxicant and is readily absorbed through intact skin, requiring careful PPE and exposure control. Full hazard detail is in the Safety section below.

Typical commercial specification
ParameterTypical value
AppearanceColourless liquid
Assay99.8% min (fibre/pharma grade)
Water content< 0.1%
Dimethylamine contentWithin producer specification

Important: the figures above are indicative of commercial material and are offered for planning only. The batch certificate of analysis is the governing document.

Physical & chemical properties
PropertyValue
Physical stateColourless, high-boiling liquid
Boiling point153 °C
Melting point-61 °C
Density0.944 g/cm³
Water solubilityFully miscible
Flash point58 °C (combustible)

Physical constants compiled from public reference data for CAS 68-12-2 and rounded for readability. Treat them as orientation, not as a specification.

Applications

Where our customers put DMF to work

The high-performance aprotic solvent behind acrylic/spandex fibre and pharmaceutical synthesis.

Acrylic fibre spinning

The principal solvent for wet- and dry-spinning polyacrylonitrile into acrylic textile fibre.

  • Fibre-grade specification
  • Bulk & drum supply
  • Technical desk review on request

Spandex (elastane) fibre

The dominant spinning solvent for polyurethane-based spandex/elastane fibre production.

  • Fibre-grade specification
  • Documented batch traceability
  • Contract & spot supply

Pharmaceutical synthesis

A widely used reaction solvent and reagent (via Bouveault and Vilsmeier-Haack reactions) in API synthesis.

  • Pharma-grade specification
  • Full analytical documentation available
  • Retained sample held against the lot

Polyurethane & vinyl coatings

Used as a solvent in polyurethane and vinyl coating and adhesive formulations.

  • Documented batch traceability
  • Technical desk review on request

Agrochemical synthesis

Used as a reaction solvent in agrochemical active-ingredient manufacturing.

  • Research & process-scale quantities
  • Full documentation supplied

Contract & scheduled supply

Fibre and pharmaceutical plants running continuous consumption are supported with scheduled bulk delivery.

  • Annual contracts with scheduled call-off
  • Price held across the contract period
  • Second source held in reserve
Buying from Chelora

How we supply Dimethylformamide

Chelora Chemicals is a supplier and sourcing partner, not a manufacturer. Purity and trace-amine content are critical to fibre-spinning and pharmaceutical-synthesis consistency — that shapes how we manage this line.

We place your order with whichever qualified producer best matches your required grade, your price point and your delivery window, and confirm your jurisdiction's import and reproductive-toxicant labelling requirements before booking.

We keep a second qualified source on this line, so a single-plant disruption never becomes your production problem.

  • Purity and trace-amine content confirmed before we quote. Consistency matters to downstream fibre-spinning and pharmaceutical-synthesis quality.
  • UN 2265 documentation managed end to end. Classification, labelling and carrier compliance confirmed before booking.
  • Scheduled call-off scheduling. We hold contracted tonnage and release it against your consumption calendar.
  • Batch traceability to the producing plant. Full chain of custody documentation on request.
  • Export machinery handled in-house. Classification, approved packing, labelling, freight booking and customs paperwork are ours to manage.
  • Fibre-grade and pharma-grade both sourced. Matched precisely to your end-use specification.
Packing & logistics

Packed the way your plant receives it

Drum, tote or bulk tank — tell us your preferred format and we will quote and classify to it.

Drums

200-210 litre drums

Steel drums for smaller-volume orders and trial quantities.

IBC totes

~1,000 litre totes

Returnable or one-way IBC totes sized for mid-volume converter orders.

Bulk ISO tank / flexi-tank

Large-volume bulk shipment

ISO tank or flexi-tank bulk shipment for continuous-consumption fibre and pharmaceutical plants.

FOB · CIF · CFR · DDP

Incoterms to suit you

Quoted on the Incoterm your purchasing team works to, with documentation filed before booking.

Small trial packs

Trial / sample quantities

Small packs dispatched for process trials before a commercial order is placed.

Scheduled release

Contracted call-off supply

We hold contracted tonnage and release it against your consumption calendar.

Safety, storage & handling

Reproductive toxicant — handle accordingly

DMF is suspected of damaging fertility and the unborn child, is readily absorbed through skin, and causes eye irritation. The summary below is orientation only — the safety data sheet supplied with your specific batch is the authoritative document.

GHS Signal word: Danger

Classified hazards

  • H226Flammable liquid and vapour.
  • H312+H319+H332Harmful in contact with skin, causes eye irritation, harmful if inhaled.
  • H360DMay damage the unborn child.

Avoid any skin contact. DMF is readily absorbed through intact skin, which is a major route of occupational exposure; always read the SDS issued with your specific batch and use impermeable gloves rated for DMF specifically (many common glove materials are not protective).

Storage

Store in tightly closed containers in a cool, dry, well-ventilated area, away from heat, sunlight, strong oxidisers and strong acids/bases.

Handling

Use DMF-rated impermeable gloves, eye/face protection and adequate ventilation (local exhaust where concentrations may build). Avoid any skin contact, inhalation and ingestion; alcohol consumption should be avoided around exposure periods, as DMF can potentiate alcohol intolerance.

Transport

Shipped as UN 2265 (N,N-Dimethylformamide), a flammable liquid. We confirm and document exact classification for your specific shipment and destination.

Quality assurance

Every batch, documented

We verify documentation before dispatch so there are no surprises at your incoming-goods bench.

Specification agreed

Assay, water content and trace-amine content confirmed against your process requirement before order placement.

Producer batch testing

The producing plant tests each batch against the agreed specification before release.

Documentation review

COA, SDS and transport paperwork checked by our desk before the shipment is booked.

Traceable dispatch

Each shipment is traceable to its producing batch, with full chain-of-custody records on request.

Production background

How DMF is made

DMF is produced industrially by the reaction of dimethylamine with carbon monoxide under catalytic conditions, or alternatively by the reaction of dimethylamine with methyl formate. The crude product is purified by distillation to the assay required for fibre-spinning or pharmaceutical-grade use.

We do not publish operating process parameters here; this is background only. Full technical documentation accompanies every shipment, and any process-specific detail you need is best confirmed directly with our technical desk.

Quick reference
Chemical familyAprotic amide solvent
Functional groupsFormamide (amide) group
ReactivityVilsmeier-Haack and Bouveault reagent; excellent polymer-dissolving aprotic solvent
Related compoundsAcrylonitrile (acrylic fibre route), Dimethylacetamide (related amide solvent)
Frequently asked

Dimethylformamide, answered

What is Dimethylformamide used for?
DMF is used mainly as the spinning solvent for acrylic and spandex fibre, as a reaction solvent and reagent in pharmaceutical and agrochemical synthesis, and in polyurethane/vinyl coating formulations.
How is Dimethylformamide made?
DMF is produced by the reaction of dimethylamine with carbon monoxide under catalytic conditions, or alternatively with methyl formate, followed by distillation purification.
Is Dimethylformamide hazardous?
Yes. DMF is suspected of damaging the unborn child, is readily absorbed through intact skin, and is harmful if inhaled or in contact with skin. It ships as UN 2265. Full regulatory documentation accompanies every consignment.
What grade do you supply?
Fibre-grade and pharmaceutical-grade DMF to the assay and trace-impurity levels your process requires. Tell us your end use and we will quote against the correct specification.
What packing do you offer?
Drums, IBC totes, and bulk ISO tank or flexi-tank shipment, sized to fibre and pharmaceutical-plant order volumes.
Do you manufacture this yourself?
No - Chelora Chemicals is a supplier and sourcing partner, not a manufacturer. We place your order with whichever qualified producer fits your specification and timeline, and hold a second source in reserve.
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