Piperidine
A saturated heterocyclic amine: piperidine's six-membered ring carries its nitrogen internally, giving it the secondary-amine basicity and reactivity that make it a workhorse reagent across rubber, synthesis and pharmaceutical chemistry.
Chelora Chemicals supplies piperidine to rubber, fine-chemical and pharmaceutical-intermediate manufacturers worldwide, with full GHS documentation on every consignment. Regulatory status varies by jurisdiction — please confirm your own compliance obligations before ordering.
Product identity
- CAS Number
- 110-89-4
- IUPAC name
- Piperidine
- Molecular formula
- C₅H₁₁N
- Molecular weight
- 85.150 g/mol
- Boiling point
- 106 °C
- Melting point
- -7 °C
- UN Number
- UN 2401
- HS Code
- 2933 32*
* Piperidine is subject to regulatory controls in a number of jurisdictions. Confirm current import/export compliance requirements for your destination with your own regulatory affairs team before ordering.
What Piperidine is used for
Piperidine is a colourless liquid with a strong, pungent amine-like odour, built on a saturated six-membered ring containing one nitrogen atom. As a secondary cyclic amine it is a strong, non-nucleophilically hindered base widely used across organic synthesis.
Piperidine serves as the precursor to rubber-vulcanization accelerators, as a solvent and base in reactions such as the Stork enamine alkylation (converting ketones to reactive enamines), as the standard reagent for Fmoc deprotection in peptide synthesis, in DNA sequencing chemistry, and as a building block in pharmaceutical synthesis, including the insect repellent icaridin.
A note on regulatory status
Because of its history as a chemical of concern in certain regulatory frameworks, piperidine is subject to controlled-substance precursor regulations in a number of jurisdictions. We supply it only for legitimate industrial and research use and expect buyers to confirm and meet their own compliance obligations; our documentation desk can support the paperwork this requires.
Where it sits among amine ring structures
- Cyclohexylamine amine attached to a carbocyclic ring. See that page.
- Piperidine (this product) nitrogen inside a saturated six-membered ring — secondary amine.
- Piperazine two nitrogens inside the ring — a related heterocyclic diamine. See that page.
| Parameter | Typical value |
|---|---|
| Appearance | Colourless liquid |
| Assay | 99.0% min |
| Water content | 0.3% max |
| Colour (Hazen) | 10 max |
Important: the figures above are indicative of commercial material and are offered for planning only. The batch certificate of analysis is the governing document.
| Property | Value |
|---|---|
| Physical state | Colourless liquid; pungent amine odour |
| Boiling point | 106 °C |
| Melting point | -7 °C |
| Density | 0.862 g/mL |
| Water solubility | Miscible |
| Amine class | Saturated heterocyclic secondary amine |
Physical constants compiled from public reference data for CAS 110-89-4 and rounded for readability. Treat them as orientation, not as a specification.
Where our customers put this amine to work
A heterocyclic base valued across synthesis, rubber and pharmaceutical chemistry.
Rubber-accelerator precursor
A precursor in the manufacture of dithiuram-type rubber-vulcanization accelerators.
- Technical grade specification
- Bulk & drum supply
- Technical desk review on request
Synthesis solvent & base
Used as a reaction solvent and strong secondary-amine base, including in enamine-forming reactions.
- Technical-grade specification
- Documented batch traceability
- Contract & spot supply
Peptide-synthesis reagent
The standard reagent for Fmoc deprotection steps in solid-phase peptide synthesis.
- Research and process-scale quantities
- Full analytical documentation available
- Retained sample held against the lot
DNA sequencing chemistry
Used in laboratory reagent formulations supporting DNA sequencing protocols.
- Technical grade specification
- Documented batch traceability
- Technical desk review on request
Pharmaceutical building block
A starting material in pharmaceutical synthesis, including the insect repellent icaridin.
- Bulk tank or drum supply
- Full documentation supplied
- Technical desk review on request
Contract & scheduled supply
Fine-chemical and pharmaceutical-intermediate plants running continuous consumption are supported with scheduled bulk delivery.
- Annual contracts with scheduled call-off
- Price held across the contract period
- Second source held in reserve
How we supply Piperidine
Chelora Chemicals is a supplier and sourcing partner, not a manufacturer. Piperidine's regulated status means end-use declaration and documentation matter as much as price — that shapes how we manage this line.
We place your order with whichever qualified producer best matches your required grade, your price point and your delivery window, and we require a clear statement of legitimate end use before booking.
We keep a second qualified source on this line, so a single-plant disruption never becomes your production problem.
- End-use declaration required. We confirm legitimate industrial or research use before accepting an order.
- UN 2401 logistics managed end to end. Classification, labelling and carrier compliance confirmed before booking.
- Regulatory documentation filed correctly. Every shipment carries the correct hazard and compliance declarations.
- Scheduled call-off scheduling. We hold contracted tonnage and release it against your consumption calendar.
- Batch traceability to the producing plant. Full chain of custody documentation on request.
- Export machinery handled in-house. Classification, approved packing, labelling, freight booking and customs paperwork are ours to manage.
Packed the way your plant receives it
Drum, IBC or bulk tank — tell us your preferred format and we will quote and classify to it.
200 L / 55 USG
Standard steel drums rated for UN 2401-classified liquid storage and transport.
Intermediate bulk containers
For mid-volume orders where drum handling becomes a logistics burden.
Synthesis-plant bulk volumes
Bulk liquid transport sized to continuous fine-chemical or rubber-plant consumption.
Incoterms to suit you
Quoted on the Incoterm your purchasing team works to, with documentation filed before booking.
Trial / sample quantities
Small packs dispatched for research trials once end use is confirmed.
Contracted call-off supply
We hold contracted tonnage and release it against your consumption calendar.
Flammable, toxic, and a regulated chemical
Piperidine's combination of flammability and toxicity makes containment and PPE the central handling concerns. It is also a regulated chemical in a number of jurisdictions. The summary below is orientation only — the safety data sheet supplied with your specific batch is the authoritative document.
Classified hazards
H225Highly flammable liquid and vapour.H311Toxic in contact with skin.H314Causes severe skin burns and eye damage.H331Toxic if inhaled.
Always read the SDS issued with your specific batch. Eliminate ignition sources; handle with chemical-resistant gloves, splash goggles and adequate ventilation. Regulatory compliance documentation accompanies every order.
Storage
Store in tightly closed containers away from heat, sparks and open flame, in a well-ventilated area rated for highly flammable liquids, with access controlled per your site's regulated-chemical procedures.
Handling
Use with local exhaust ventilation and bond/ground equipment during transfer to control static discharge. Minimise inhalation and skin contact with appropriate PPE.
Transport
Shipped as UN 2401 in accordance with its flammable/toxic classification, with any additional regulated-chemical transport documentation your jurisdiction requires.
Every batch, documented
We verify documentation before dispatch so there are no surprises at your incoming-goods bench.
End use confirmed
Legitimate industrial or research use confirmed before order placement.
Producer batch testing
The producing plant tests each batch against the agreed specification before release.
Documentation review
COA, SDS and regulatory/transport paperwork checked by our desk before the shipment is booked.
Traceable dispatch
Each shipment is traceable to its producing batch, with full chain-of-custody records on request.
How piperidine is made
Piperidine is produced industrially by the catalytic hydrogenation of pyridine, giving the saturated heterocyclic amine after purification and fractional distillation.
We do not publish operating process parameters here; this is background only. Full technical, safety and regulatory documentation accompanies every shipment, and any process-specific or compliance detail you need is best confirmed directly with our technical desk.
| Chemical family | Saturated heterocyclic amine |
|---|---|
| Ring structure | Six-membered, one nitrogen (azinane) |
| Reactivity | Strong secondary-amine base; forms enamines, amides and salts |
| Related compounds | Piperazine (two-nitrogen analog), Cyclohexylamine (carbocyclic analog) |
Explore the wider amine range
Piperidine, answered
What is piperidine used for?
How does piperidine differ from cyclohexylamine?
Is piperidine hazardous?
What grade do you supply?
What packing do you offer?
Do you manufacture this yourself?
- Need a related amine? See our Piperazine and Morpholine pages.
Get a quote on Piperidine today
Send us your required grade, pack size, delivery window and intended end use. We will come back with a firm quote, lead time and full documentation.