2,5-Dichloroaniline
2,5-Dichloroaniline is a dichlorinated aniline whose principal outlet is azo pigment manufacture — it is the diazo component behind Pigment Yellow 10 and related colourants used in printing inks, plastics and coatings. It also serves in dye and select agrochemical intermediate chemistry.
Chelora Chemicals supplies 2,5-dichloroaniline to pigment manufacturers, dye houses and fine chemical producers worldwide, in bags, drums and container quantities, with a batch COA and GHS safety data sheet on every consignment.
Product identity
- CAS Number
- 95-82-9
- IUPAC name
- 2,5-Dichloroaniline
- Molecular formula
- C6H5Cl2N
- Molecular weight
- 162.01 g/mol
- EC / EINECS
- 202-455-2
- SMILES
- Nc1cc(Cl)ccc1Cl
- HS Code
- 2921 42*
* Confirm the exact HS heading with your customs broker — classification of halogenated aniline derivatives varies between destination tariffs.
What 2,5-Dichloroaniline is used for
2,5-Dichloroaniline is aniline carrying chlorine atoms at the 2 and 5 ring positions. The two electron-withdrawing chlorines deactivate the ring and steady the diazonium salt formed on diazotisation, giving a diazo component that couples cleanly to naphthol AS derivatives. That reaction is the industrial route to Pigment Yellow 10 and related monoazo pigments used across printing inks, plastics masterbatch and industrial coatings.
It is produced industrially by hydrogenation of 1,4-dichloro-2-nitrobenzene, and — like most of the dichloroaniline isomer family — is bought almost entirely as a captive pigment or dye intermediate rather than sold on as a finished product.
Why the isomer matters
Dichloroaniline has six possible isomers, and each gives a distinct chromophore and downstream chemistry. A substitution downstream is not recoverable:
- 2,5-Dichloroaniline (CAS 95-82-9) — this product. The isomer behind Pigment Yellow 10 and related yellow azo pigment chemistry.
- 3,4-Dichloroaniline (CAS 95-76-1) — the isomer used for phenylurea herbicides (diuron, linuron) and carbanilide antimicrobials. See our 3,4-dichloroaniline page.
- 2,4-Dichloroaniline (CAS 554-00-7) and 2,3-/3,5-dichloroaniline — further isomers used across narrower dye, pigment and agrochemical routes.
If your purchase order simply says "dichloroaniline," quote us the CAS number and we will confirm the correct material before the order is placed. We supply several dichloroaniline isomers and related chloroanilines across our full product catalogue.
Appearance and handling character
2,5-Dichloroaniline ships as a colourless to off-white crystalline solid melting around 48 °C — a solid in temperate storage, but liable to soften in an uncooled container on a tropical routing. It is insoluble in water and dissolves in most organic solvents. Like other primary aromatic amines it can darken slightly on prolonged exposure to air and light. Read the safety section before planning any handling: this material is an acute toxicant by all three exposure routes and carries a repeated-dose organ toxicity entry, and that should shape your controls from the outset.
| Parameter | Typical value |
|---|---|
| Appearance | Colourless to off-white crystals |
| Assay (GC) | 99.0% min |
| Moisture (KF) | 0.3% max |
| Melting range | 47 – 50 °C |
| Total isomeric impurities | 1.0% max |
| Colour (molten, APHA) | Reported per batch |
Important: the figures above are indicative of commercial grade material and are offered for planning only. The batch certificate of analysis is the governing document. If your pigment process demands a tighter assay, an isomer limit or a colour ceiling, send us the specification and we will quote against it rather than against a generic grade.
| Property | Value |
|---|---|
| Physical state | Crystalline solid at ambient |
| Melting point | ≈ 47 – 50 °C |
| Boiling point | ≈ 244 – 251 °C |
| Flash point | ≈ 139 °C |
| Relative density | ≈ 1.54 |
| Water solubility | Insoluble to very sparingly soluble |
| Organic solubility | Soluble in alcohols, ketones & aromatic solvents |
| Odour | Faint, amine-like |
Physical constants compiled from public reference data for CAS 95-82-9 and rounded for readability. Treat them as orientation, not as a specification.
Where our customers put this molecule to work
2,5-Dichloroaniline's volume is concentrated in azo pigment manufacture, with secondary demand from dye and fine chemical producers.
Azo pigments (Pigment Yellow 10)
The defining outlet. Diazotised 2,5-dichloroaniline couples onto naphthol AS derivatives to build Pigment Yellow 10 and related monoazo yellow pigments used in printing inks, plastics and industrial coatings.
- Diazo component in monoazo pigment synthesis
- Shade and fastness depend directly on purity
- See our full aniline intermediate range
Dye intermediate chemistry
The same diazo chemistry extends into disperse and azo dye synthesis, where the dichlorinated ring gives shade and fastness properties distinct from a plain or mono-chlorinated aniline.
- Diazo component in specialty dye chemistry
- Isomer purity shows up directly as off-shade
- See also 3,4-dichloroaniline
Agrochemical intermediates
2,5-Dichloroaniline and related dichlorinated anilines are used in select crop-protection intermediate chemistry, where the specific chlorination pattern is part of the target structure.
- Custom agrochemical intermediate synthesis
- Moisture and isomer purity are critical
- See our agrochemical intermediate range
Pharmaceutical & fine chemical intermediates
The 2,5-dichlorophenyl fragment appears in select pharmaceutical and specialty chemical synthesis routes, installed through amide formation or N-arylation using this aniline as the starting amine.
- Amide and urea formation
- Heterocyclic ring construction
- See also ortho anisidine
Fine & specialty synthesis
A well-characterised, deactivated aryl amine building block for custom amides, azo dyes and ligand work where the 2,5-dichloroaniline pattern is specifically required.
- Custom amide and azo dye formation
- Ligand and coordination chemistry
- Available in trial and laboratory quantities
Contract & scheduled supply
Pigment plants run to campaign, not to a calendar month. Most 2,5-dichloroaniline buyers want tonnage released against a production plan rather than in one shipment. We hold inventory and release it to your schedule.
- Annual contracts with scheduled call-off
- Price held across the contract period
- Second source held in reserve
How we supply 2,5-Dichloroaniline
Chelora Chemicals is a supplier and sourcing partner, not a manufacturer. We own no dichloroaniline plant — and for a specification-sensitive pigment intermediate like this one, that independence works in your favour. We are never obliged to push you whatever a captive unit happens to be running that month.
Instead we place your order with whichever qualified producer best matches your assay, your isomer tolerance, your price point and your delivery window.
We keep a second qualified source on this line. When a plant goes down for maintenance, your campaign switches source rather than stalling.
- Specification read against the CAS first. We confirm you need 95-82-9 and not one of the other five dichloroaniline isomers before we quote a price.
- Batch COA shared before dispatch. You approve the assay, moisture and isomer profile against your own spec while the material is still in our warehouse.
- Hazard status stated up front. This material is toxic by all three exposure routes and carries a repeated-dose organ toxicity entry, and we say so at enquiry stage — not in the small print of a document pack that arrives with the goods.
- Pre-shipment samples for qualification. New account or new source, your R&D or pigment lab runs a coupling trial before the full quantity ever moves.
- Packing chosen for your climate. With a melting point just above 48 °C, pack format and stowage matter on a tropical routing. We plan both with you.
- Export machinery handled in-house. Hazard classification, UN-approved packing, labelling, freight booking and customs paperwork are ours to manage.
- Consolidation onto one bill of lading. Ship 2,5-dichloroaniline alongside other intermediates from our range — one invoice, one shipment, one counterparty.
Packed the way your plant receives it
Pack format drives your landed cost and your handling effort. Tell us how it will be charged at your end and we will quote the format that suits your operation.
Multi-wall paper & PE bags
Laminated multi-wall bags with an inner liner, palletised and shrink-wrapped. The default for LCL movements and for plants charging batch-wise by hand.
Fibre & HDPE drums
UN-certified drums with liner for longer sea transits and humid destinations. Better protection against moisture pick-up and caking than bagged material.
Jumbo / FIBC bags
Bulk bags with liner for high-volume users with mechanical charging. Fewer handling movements, lower operator contact and materially lower packing cost per kilo.
Samples & trial packs
Laboratory samples and pilot quantities dispatched by courier so your R&D or pigment lab can qualify the grade before committing to campaign volume.
Incoterms to suit you
Quoted on the Incoterm your purchasing team works to. Ocean, air and road freight arranged end-to-end with documentation filed before booking.
Campaign despatch
Pigment production runs to campaign. We hold contracted tonnage and release it against your production calendar instead of landing it all at once.
Handle this as a classified acute toxicant
This is the point on the page that matters most. 2,5-dichloroaniline is toxic by ingestion, skin contact and inhalation, carries a repeated-dose organ toxicity entry, and is very toxic to aquatic life with long-lasting effects. The summary below is orientation only — the safety data sheet supplied with your consignment is the authoritative document and should govern your risk assessment, PPE selection, exposure monitoring and emergency planning.
Classified hazards
H301Toxic if swallowed.H311Toxic in contact with skin.H331Toxic if inhaled.H373May cause damage to organs through prolonged or repeated exposure.H410Very toxic to aquatic life with long lasting effects.
Hazard statements reflect the harmonised GHS classification commonly published for CAS 95-82-9 (GHS06 Toxic, GHS08 Health hazard, GHS09 Environmental hazard). Supplier classifications may differ in detail; always read the SDS issued with your specific batch.
Spill & emergency orientation
Plan your response before the pallet arrives, not after a bag splits. The points below are orientation for your emergency planners — sections 4, 5 and 6 of the SDS are the authoritative instructions and should be posted at the point of use.
- Sweep, do not hose. The material is very toxic to aquatic life with long-lasting effects. Collect spilled solid mechanically into a labelled container; never wash it to a drain.
- Suppress dust. Dry sweeping of a fine solid generates an inhalable aerosol — use vacuum collection or dampen carefully in line with the SDS.
- Assume skin absorption. Contaminated clothing is a continuing exposure route — remove it immediately and wash the skin thoroughly.
- Have the SDS with the casualty. Chloroanilines can cause methaemoglobinaemia, and the treating clinician needs the product identity and CAS number in hand.
- Monitor after significant exposure. H373 flags a specific target organ risk on repeated exposure — that is a decision for your occupational health provider to build into a surveillance programme.
Storage
- Cool, dry, well-ventilated store, away from direct sunlight and heat sources. The melting point is only about 48 °C, so an uncooled store in a hot climate can soften or fuse the contents.
- Keep containers tightly closed. Air and moisture pick-up affect colour over long storage, and an open bag also picks up moisture.
- Segregate from oxidising agents, strong acids and acid chlorides. As a primary aromatic amine it reacts exothermically with acylating and oxidising reagents.
- Access-controlled storage. Restricting who can reach an acute toxicant is part of the control, not an administrative nicety.
- Shelf life is typically 12–24 months in sealed original packing under these conditions. Re-assay before use after long storage.
Handling & PPE
- Design exposure out. Closed transfer and mechanical charging first, local exhaust ventilation second, PPE last — the standard hierarchy of control for a fine toxic powder.
- Skin protection is the priority. Chloroanilines are absorbed through intact skin — use chemical-resistant gloves and coveralls, not just splash protection.
- Respiratory protection where dust may be generated — particularly when charging reactors or emptying a bulk bag — per your own exposure assessment.
- Health surveillance where indicated. The H373 (organ toxicity) entry means some sites build periodic monitoring into their occupational health programme for regular handlers.
- Never discharge to drain or watercourse. H410 applies — collect spills as solid waste and dispose of them as regulated chemical waste.
Transport
2,5-Dichloroaniline moves as regulated cargo. We classify each consignment, apply UN-approved packaging and labelling, and file the dangerous-goods declaration before the booking is made. The applicable UN number, class and packing group are stated on your shipping documents and SDS — ask us for the current DG paperwork when you plan the shipment.
What travels with every consignment
A chemical shipment is only as good as the file that travels with it. Verifying what the source plant sends is precisely the work you are buying from a supplier.
Certificate of Analysis
Batch-specific assay by GC, moisture by Karl Fischer, appearance, melting range and impurity profile — checked against your purchase specification before we release the goods.
GHS Safety Data Sheet
Full 16-section SDS in GHS format covering hazards, exposure controls, handling, storage, spill response, toxicology and disposal — issued in the language your destination requires.
Dangerous Goods Declaration
UN number, hazard class, packing group and IMDG or IATA declaration prepared and filed before the container is booked, with correctly marked and labelled packaging.
Certificate of Origin
Chamber-attested where required, plus preferential-origin forms where a trade agreement gives your import duty relief at the destination.
Third-party inspection
SGS, Intertek or Bureau Veritas sampling and inspection arranged on request before loading, giving you independent verification of what actually ships.
Retained & pre-shipment samples
Pre-shipment samples carry the same COA as the commercial lot, so what your laboratory qualifies is exactly what arrives. Retention samples held against the batch.
Why two chlorines give a steadier diazonium salt
Two electron-withdrawing chlorines on the ring do more than change the melting point — they steady the diazonium salt formed on diazotisation, giving cleaner, more reliable coupling chemistry than a mono-chlorinated or unsubstituted aniline. The route below is the general industrial pattern, not a process disclosure.
Start with the aniline
2,5-Dichloroaniline provides a primary aromatic amine deactivated by two chlorine atoms, giving a diazonium salt that is more stable and easier to handle than one from a less-substituted aniline.
Diazotise
Sodium nitrite in acid at low temperature gives the diazonium salt cleanly, with the two chlorines helping suppress side reactions during this step.
Couple onto naphthol AS
The diazonium salt is coupled onto a naphthol AS component to build the finished monoazo pigment, such as Pigment Yellow 10.
Finish the pigment
The crude pigment is filtered, washed and finished — particle size, crystal form and surface treatment are tuned to the application, whether printing ink, plastics or coatings.
Why feed quality carries through the whole route
The whole value of this route lies in shade and fastness, so anything in the feed that competes for the diazotisation chemistry, or carries its own colour, follows the material into the finished pigment:
- Isomeric dichloroanilines diazotise in parallel and give structurally similar but off-shade chromophores — a real problem in colour-critical pigment work.
- Residual water can complicate diazotisation control at the low temperatures this reaction typically runs at.
- Oxidation products dull a finished shade and can show as off-colour in an otherwise near-colourless solid.
- Heavy residues concentrate in mother liquors and can affect particle size and crystal habit in the finished pigment.
That chain of consequences is the reason we quote against your written specification rather than a generic "99% technical" grade, and the reason the batch COA is shared for approval before dispatch rather than sent with the invoice.
| Isomer | Principal outlet |
|---|---|
| 2,5-Dichloroaniline CAS 95-82-9 — this product | Pigment Yellow 10 Azo pigments & dyes |
| 3,4-Dichloroaniline CAS 95-76-1 | Diuron, linuron, propanil Carbanilide antimicrobials |
| 2,4-Dichloroaniline CAS 554-00-7 | Dye & agrochemical intermediates |
If your route calls for a different isomer, we supply those as well — see our full product catalogue. Send the CAS number and we will confirm the correct material before quoting.
What actually moves the price of this intermediate
2,5-Dichloroaniline is not a commodity with a screen price. Knowing what drives the quote helps you time a purchase and read whether an offer is realistic.
Pigment demand cycles
Printing ink, plastics masterbatch and coatings demand pull on the same aniline through the year, tracking those end industries' own production cycles.
- Quote early for campaign tonnage
- Spot buying at peak costs materially more
- Contracted call-off smooths the exposure
Upstream feedstock
The route back to 2,5-dichloroaniline runs through chlorobenzene, nitration and selective reduction. Movements in benzene, chlorine and hydrogen feed through to the aniline within a quarter or so.
- Chlorine and benzene set the floor
- Catalyst and energy costs weigh on the reduction step
- We flag feedstock-driven moves in the quote
Regulatory pressure
Acute toxicity classification raises the compliance cost of producing, storing and moving this material. That cost sits inside the price.
- Handling obligations vary by jurisdiction
- Some markets restrict certain end uses
- We check destination rules before quoting
Pack format
Cost per kilo falls from 25 kg bags to drums to jumbo bags — and with an acute toxicant, bulk bags also cut the number of times an operator opens a pack.
- Small bags carry the highest packing cost
- FIBC is cheapest per kilo at volume
- Less manual handling means less exposure
Freight & DG surcharges
This is regulated cargo, so ocean freight carries a hazardous surcharge and space is tighter than for general cargo. Destination and Incoterm move landed cost as much as the ex-works price does.
- Compare on landed cost, not ex-works
- DG space books out ahead of peak season
- We quote FOB, CIF, CFR or DDP as you prefer
Source availability
A plant turnaround or an environmental inspection can take capacity offline at short notice. Single-sourced buyers feel this hardest.
- We hold a second qualified source on this line
- Qualify the alternate before you need it
- Ask us about dual-source contracts
| If your end use is… | Specify |
|---|---|
| Azo pigments (e.g. Pigment Yellow 10) | Colour ceiling, tight isomer limit, low insolubles |
| Specialty dye chemistry | Colour ceiling, controlled impurity profile |
| Agrochemical synthesis | High assay; moisture the critical parameter for several routes |
| Pharmaceutical chain | Tight isomer limit; metals and residues reported |
| Laboratory / R&D | Small pack, high purity, full analytical pack |
Not sure which column you are in? Describe the reaction you are running and our technical desk will recommend the grade — including telling you when a cheaper specification would do the job just as well.
Support that goes beyond shipping the bag
What our technical desk will do
- Match a grade to your reaction. Tell us the coupling or reaction you are running and we will recommend the specification — and say so plainly when a tighter, costlier grade would add nothing.
- Be straight about the hazard profile. We state the acute toxicity classification at enquiry stage so your EHS team can price the controls into the decision, rather than meeting it for the first time on the label.
- Advise on handling and storage for your site conditions — dust control for a fine solid looks different in a humid coastal plant than in a dry inland one.
- Review your specification before it goes into a contract, so you are not locked into a limit that no plant can consistently hit.
Regulatory & compliance notes
- Acute toxicant obligations are jurisdiction-specific. Several regimes impose exposure limits, health surveillance and record retention for chemicals with this hazard profile. Confirm what applies at your site before the first delivery.
- Import controls vary by destination. Some jurisdictions apply registration, licensing or end-use declaration requirements to this material. We check the destination rules before quoting, not after you have raised the PO.
- Chemical inventory listings differ between regions. Confirm your obligations under the applicable inventory regime for your import volume — we will supply the identity data you need for that filing.
- Downstream article restrictions can apply to certain colourant and consumer applications. Your regulatory team should confirm the finished-article position for the end use you have in mind.
None of the above is legal advice — your own regulatory affairs team owns the final compliance position for your import and your workplace. What we commit to is giving you accurate product identity data, an honest statement of the hazard classification and complete documentation to work from.
From enquiry to delivered pallet
Send the specification
Product name or CAS 95-82-9, the assay and impurity limits you work to, quantity, pack preference and destination port.
Receive a firm quote
Pricing, lead time, packing and Incoterm confirmed in writing within 24 hours — our sourcing desk is staffed around the clock.
Qualify and approve
Sample dispatched if you are qualifying a new source. Batch COA shared for your approval before the material is released.
Ship and track
DG classification filed, freight booked, export documents issued, and the consignment tracked through transit and clearance to your plant.
Often bought alongside this grade
Consolidate several intermediates onto one shipment and one invoice. These are the anilines and aromatics our pigment, dye and fine chemical customers most often order in the same programme. Each of the following is part of our wider aniline intermediate range — browse the full product catalogue for current availability and specification sheets.
What buyers ask us about 2,5-Dichloroaniline
Is this material a classified carcinogen?
Can I use another dichloroaniline isomer instead?
What purity do you normally supply?
What is the minimum order quantity?
How long does delivery take?
The material arrived caked or partly fused. Is it off-spec?
How should we store it, and what is the shelf life?
Is this a dangerous good? What paperwork comes with it?
- Batch certificate of analysis
- GHS-format safety data sheet
- Dangerous-goods declaration with UN number, class and packing group
- Commercial invoice, packing list and bill of lading or airway bill
- Certificate of origin and any destination-specific forms
Do you supply to my country?
Do you manufacture this yourself?
Can you hold stock against a production plan?
Request pricing on 2,5-Dichloroaniline
Send your required assay, quantity, pack format and destination port. Our sourcing desk is available 24 hours a day, 7 days a week, and comes back with pricing, lead time and packing options — whether that is a single trial bag or a contracted container programme for the year.