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Triethylenetetramine

TETA · Trien · CAS 112-24-3

The four-amine member of the ethyleneamine family: TETA's extended nitrogen chain makes it a stronger epoxy crosslinker than its lower homologs, and the chemical basis of a life-saving copper-chelating therapy.

Chelora Chemicals supplies triethylenetetramine to epoxy, coordination-chemistry and specialty manufacturers worldwide, with full GHS documentation on every consignment.

  • Epoxy crosslinking hardener
  • "Trien" coordination ligand
  • Trientine (Wilson's disease therapy) backbone
  • Specialty synthesis
  • Corrosive — handle accordingly
  • UN 2259

Product identity

CAS Number
112-24-3
IUPAC name
N,N'-Bis(2-aminoethyl)ethane-1,2-diamine
Molecular formula
C₆H₁₈N₄
Molecular weight
146.238 g/mol
Boiling point
266.6 °C
Melting point
-34.6 °C
UN Number
UN 2259
HS Code
2921 29*

* Confirm the current HS classification and import regulatory status for your destination with your own regulatory affairs team.

146.24g/mol molecular weight
266.6 °CBoiling point
-34.6 °CMelting point
0.982g/mL density
Product overview

What Triethylenetetramine is used for

Triethylenetetramine is a colourless liquid (older samples may appear yellowish from mild air oxidation) with a fishy, ammoniacal odour, extending the ethyleneamine chain to four nitrogen sites across three ethylene bridges. That extended backbone gives TETA stronger crosslinking power than the lower-amine homologs.

Industrially, TETA is used primarily as a crosslinking hardener for epoxy resins. In chemistry, it serves as a tetradentate ligand — known as "trien" — forming stable complexes with transition metals for research and catalysis. Its hydrochloride salt, trientine, is a recognised pharmaceutical chelating agent that removes excess copper from the body, used to treat Wilson's disease in patients who are intolerant to penicillamine.

Where it sits in the ethyleneamine family

  • Diethylenetriamine (DETA) three amine groups — epoxy hardener and chelate backbone. See that page.
  • Triethylenetetramine (this product) four amine groups — stronger crosslinker, trientine backbone.
  • Tetraethylenepentamine (TEPA) five amine groups — the next step up in viscosity and reactivity. See that page.

Appearance and handling character

Triethylenetetramine is corrosive — harmful in contact with skin, causes severe skin burns and eye damage, may cause an allergic skin reaction, and is harmful to aquatic life with long-lasting effects — a profile typical of the higher ethyleneamines.

Typical commercial specification
ParameterTypical value
AppearanceColourless to pale yellow liquid
Assay98.0% min
Water content0.5% max
Colour (Hazen)30 max

Important: the figures above are indicative of commercial material and are offered for planning only. The batch certificate of analysis is the governing document.

Physical & chemical properties
PropertyValue
Physical stateColourless to pale yellow liquid; fishy, ammoniacal odour
Boiling point266.6 °C
Melting point-34.6 °C
Density0.982 g/mL
Water solubilityFully miscible
Amine classAliphatic tetramine (ethyleneamine)

Physical constants compiled from public reference data for CAS 112-24-3 and rounded for readability. Treat them as orientation, not as a specification.

Applications

Where our customers put this tetramine to work

A four-nitrogen crosslinker spanning epoxy chemistry and coordination chemistry.

Epoxy crosslinking hardener

TETA's main industrial use — a strong crosslinking agent for epoxy resin systems.

  • Technical grade specification
  • Bulk & drum supply
  • Technical desk review on request

Coordination-chemistry ligand

A tetradentate ligand ("trien") used in forming stable transition-metal complexes.

  • Technical-grade specification
  • Documented batch traceability
  • Contract & spot supply

Trientine precursor

The chemical backbone of trientine, a pharmaceutical chelating agent used in Wilson's disease therapy.

  • Packs from 25 kg drum / bulk
  • Full analytical documentation available
  • Retained sample held against the lot

Specialty synthesis

Used wherever a tetra-functional amine building block is required in research and process chemistry.

  • Technical grade specification
  • Documented batch traceability
  • Technical desk review on request

Corrosion inhibitors

Used as an intermediate in certain corrosion-inhibitor and water-treatment formulations.

  • Research and process-scale quantities
  • Full documentation supplied
  • Technical desk review on request

Contract & scheduled supply

Epoxy and specialty-chemical plants running continuous consumption are supported with scheduled bulk delivery.

  • Annual contracts with scheduled call-off
  • Price held across the contract period
  • Second source held in reserve
Buying from Chelora

How we supply Triethylenetetramine

Chelora Chemicals is a supplier and sourcing partner, not a manufacturer. TETA's use as a strong epoxy crosslinker means amine-value consistency matters as much as price — that shapes how we manage this line.

We place your order with whichever qualified producer best matches your required grade, your price point and your delivery window.

We keep a second qualified source on this line, so a single-plant disruption never becomes your production problem.

  • Amine value confirmed before we quote. Consistency matters to downstream epoxy cure performance.
  • UN 2259 logistics managed end to end. Classification, labelling and carrier compliance confirmed before booking.
  • Aquatic-hazard documentation filed correctly. Every shipment carries the correct hazard declarations.
  • Scheduled call-off scheduling. We hold contracted tonnage and release it against your consumption calendar.
  • Batch traceability to the producing plant. Full chain of custody documentation on request.
  • Export machinery handled in-house. Classification, approved packing, labelling, freight booking and customs paperwork are ours to manage.
Packing & logistics

Packed the way your plant receives it

Drum, IBC or bulk tank — tell us your preferred format and we will quote and classify to it.

Drums

200 L / 55 USG

Standard steel drums rated for UN 2259-classified liquid storage and transport.

IBCs

Intermediate bulk containers

For mid-volume orders where drum handling becomes a logistics burden.

ISO tank / road tanker

Epoxy-plant bulk volumes

Bulk liquid transport sized to continuous epoxy-hardener plant consumption.

FOB · CIF · CFR · DDP

Incoterms to suit you

Quoted on the Incoterm your purchasing team works to, with documentation filed before booking.

25 kg / 200 kg packs

Trial / sample quantities

Small packs dispatched for process trials before a commercial order is placed.

Scheduled release

Contracted call-off supply

We hold contracted tonnage and release it against your consumption calendar.

Safety, storage & handling

Corrosive, sensitising, and harmful to aquatic life

Triethylenetetramine's combination of corrosivity and skin-sensitisation potential makes PPE and exposure control the central handling concerns. The summary below is orientation only — the safety data sheet supplied with your specific batch is the authoritative document.

GHS Signal word: Danger

Classified hazards

  • H312Harmful in contact with skin.
  • H314Causes severe skin burns and eye damage.
  • H317May cause an allergic skin reaction.
  • H412Harmful to aquatic life with long-lasting effects.

Always read the SDS issued with your specific batch. Handle with chemical-resistant gloves, splash goggles and adequate ventilation; avoid skin contact to prevent sensitisation.

Storage

Store in tightly closed containers in a cool, dry, well-ventilated area, away from strong oxidisers and acids.

Handling

Use with local exhaust ventilation. Minimise skin contact with appropriate gloves and protective clothing to prevent sensitisation. Contain any spill to prevent waterway contamination.

Transport

Shipped as UN 2259 in accordance with its corrosive classification. We confirm and document packing group and exact classification for your specific shipment and destination.

Quality assurance

Every batch, documented

We verify documentation before dispatch so there are no surprises at your incoming-goods bench.

Specification agreed

Amine value confirmed against your process requirement before order placement.

Producer batch testing

The producing plant tests each batch against the agreed specification before release.

Documentation review

COA, SDS and transport paperwork checked by our desk before the shipment is booked.

Traceable dispatch

Each shipment is traceable to its producing batch, with full chain-of-custody records on request.

Production background

How TETA is made

Triethylenetetramine is produced industrially as part of the same ethyleneamine process family as ethylenediamine and diethylenetriamine, through successive ethylene-bridge extension reactions, followed by fractional distillation to separate the ethyleneamine homologues.

We do not publish operating process parameters here; this is background only. Full technical and safety documentation accompanies every shipment, and any process-specific detail you need is best confirmed directly with our technical desk.

Quick reference
Chemical familyAliphatic tetramine (ethyleneamine)
Nitrogen sitesFour amine groups
ReactivityTetradentate nucleophile; strong epoxy crosslinker, forms chelates
Related compoundsDiethylenetriamine (lower homolog), Tetraethylenepentamine (higher homolog)
Frequently asked

Triethylenetetramine, answered

What is triethylenetetramine used for?
Triethylenetetramine (TETA) is used primarily as a crosslinking hardener for epoxy resin systems. It also serves as a tetradentate ligand in coordination chemistry, known there as 'trien'. Its hydrochloride salt, trientine, is a pharmaceutical chelating agent used to treat Wilson's disease in patients who cannot tolerate penicillamine.
How does TETA differ from DETA?
TETA extends diethylenetriamine's three-amine backbone with a fourth amine group and an additional ethylene bridge, giving it four nitrogen sites. That extra amine makes TETA an even stronger epoxy crosslinker than DETA, with a higher boiling point and viscosity.
Is triethylenetetramine hazardous?
Yes. It is harmful in contact with skin, causes severe skin burns and eye damage, may cause an allergic skin reaction, and is harmful to aquatic life with long-lasting effects. It ships as UN 2259. Full GHS documentation accompanies every consignment.
What grade do you supply?
Technical grade, typically 99%+ assay. Tell us your end use and we will quote against the correct specification.
What packing do you offer?
Drums, IBCs and bulk/ISO tank shipment, sized to epoxy-hardener and specialty-chemical order volumes.
Do you manufacture this yourself?
No - Chelora Chemicals is a supplier and sourcing partner, not a manufacturer. We place your order with whichever qualified producer fits your specification and timeline, and hold a second source in reserve.
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