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Vitamin E Acetate

DL-alpha-Tocopheryl Acetate · CAS 7695-91-2

Free Vitamin E oxidises in storage before it ever reaches a capsule. Esterifying it to the acetate solves that: a shelf-stable, oxidation-resistant liquid or powder that still delivers active Vitamin E once the ester is cleaved in the body.

Chelora Chemicals supplies USP/EP/FCC-grade Vitamin E acetate — in liquid, powder and beadlet forms — to supplement, animal-feed and cosmetic-ingredient manufacturers worldwide, with a batch COA on every consignment.

  • Liquid, powder & beadlet forms
  • USP/EP/FCC grades
  • Supplements, feed & cosmetic actives
  • Oxidation-resistant ester form
  • Not classified as hazardous
  • Not a dangerous good

Product identity

CAS Number
7695-91-2
IUPAC name
DL-alpha-Tocopheryl acetate
Molecular formula
C₃₁H₅₂O₃
Molecular weight
472.74 g/mol
EC / EINECS
231-710-0
Hazard classification
Not classified (GHS)
Physical form
Viscous liquid / powder / beadlet
HS Code
2936 28*

* Confirm the current HS classification and food/feed/cosmetic regulatory status for your destination with your own regulatory affairs team.

472.74g/mol molecular weight
0.96 g/mLDensity at 20 °C (liquid)
96 – 102%Typical assay (USP)
24 moShelf life, sealed
Product overview

What Vitamin E Acetate is used for

DL-alpha-Tocopheryl acetate is a colourless to pale yellow, viscous oil at room temperature (also supplied as a powder or beadlet for solid-dose use) — the acetate ester of synthetic Vitamin E. Free tocopherol is a strong antioxidant, but that same reactivity means it oxidises on exposure to air, light and heat during processing and storage. Esterification to the acetate removes that reactive hydroxyl group, giving a shelf-stable raw material that is cleaved back to active tocopherol by esterases once absorbed in the body.

Its principal markets are dietary supplements and multivitamin formulations, animal feed and premix manufacture, and cosmetic skin-care and hair-care formulation, where it serves as both a stable Vitamin E source and a skin-conditioning ingredient.

DL- versus D- (natural) tocopheryl acetate

  • DL-alpha-tocopheryl acetate (this product) the synthetic, racemic form — the most widely traded commercial Vitamin E raw material on cost grounds.
  • D-alpha-tocopheryl acetate the natural-source form, often commanding a premium for "natural Vitamin E" label claims; available on request as a separate specification.
  • Both are acetate esters; the difference is stereochemistry and sourcing claim, not the acetate chemistry itself.

See our wider nutraceutical range for the other vitamin intermediates we supply, including niacinamide (Vitamin B3) and folic acid (Vitamin B9).

Appearance and handling character

The liquid form is a viscous, oil-soluble liquid, essentially insoluble in water, that is considerably more oxidation-resistant than free tocopherol but still benefits from cool, dark storage and a nitrogen headspace in bulk packaging. Powder and beadlet forms are diluted, free-flowing solids suited to tableting and dry-blend use.

Typical commercial specification (USP, liquid)
ParameterTypical value
AppearanceColourless to pale yellow viscous liquid
Assay96.0 – 102.0%
Refractive index (20 °C)1.494 – 1.499
Density (20 °C)0.95 – 0.96 g/mL
Acid value0.2 max
Heavy metals10 ppm max

Important: the figures above are indicative of commercial liquid-grade material and are offered for planning only. The batch certificate of analysis is the governing document. Powder and beadlet forms carry a separate specification — tell us your preferred physical form.

Physical & chemical properties
PropertyValue
Physical stateViscous liquid at ambient (also powder/beadlet)
Boiling point224 °C at 0.3 mmHg
Water solubilityPractically insoluble
Oil/solvent solubilityMiscible with vegetable oils, soluble in most organic solvents
Oxidative stabilitySubstantially more stable than free tocopherol
Light sensitivityMild — cool, dark storage still recommended

Physical constants compiled from public reference data for CAS 7695-91-2 and rounded for readability. Treat them as orientation, not as a specification.

Applications

Where our customers put this vitamin to work

One stable Vitamin E raw material, supplied in the physical form each buyer group actually needs.

Dietary supplements

Softgel, tablet and capsule formulations drawing on liquid or beadlet forms for stable Vitamin E dosing.

  • USP/EP pharmacopoeia grades
  • Beadlet form for direct tableting
  • Small packs for formulation trials

Animal feed & premix

A standard antioxidant and Vitamin E source in poultry, swine, aquaculture and companion-animal feed premixes.

  • Feed-grade powder specification available
  • Bulk-bag and drum packing for premix houses
  • Contracted annual tonnage supported

Cosmetic & personal-care actives

A widely used antioxidant and skin-conditioning ingredient in moisturisers, serums, sun-care and hair-care formulations.

  • Cosmetic-ingredient grade on request
  • INCI-standard documentation supplied
  • Liquid form suited to emulsion systems

Food & beverage antioxidant systems

Used in some fortified foods and oils both as a Vitamin E source and a natural-leaning antioxidant for fat stability.

  • FCC food-grade documentation
  • Compliant with major fortification standards
  • Technical desk support on dosing

Nutraceutical blending

Combined with other fat-soluble vitamins (A, D, K) in multi-vitamin oil blends and premixes.

  • Custom blend formulation support
  • Compatible with standard oil carriers
  • Stability data available on request

Research & analytical use

Reference standard and small-scale formulation trial quantities with the same documentation as the commercial lot.

  • Packs from 500 g
  • Full analytical documentation available
  • Retained sample held against the lot
Buying from Chelora

How we supply Vitamin E Acetate

Chelora Chemicals is a supplier and sourcing partner, not a manufacturer. On a vitamin traded in several physical forms and two stereochemical variants, that means we match your order to the exact form your production line actually runs, not whatever a single plant happens to have.

We place your order with whichever qualified producer best matches your target form (liquid, powder, beadlet), your price point and your delivery window.

We keep a second qualified source on this line, because Vitamin E acetate is one of the highest-volume vitamin raw materials traded globally, and supply continuity matters at that scale.

  • Physical form confirmed before we quote. Liquid, powder or beadlet each suit different production lines, and we match before pricing.
  • DL- versus D- form confirmed. Synthetic and natural-source Vitamin E command different prices and label claims — we confirm which you need.
  • Nitrogen-headspace packing for liquid form. A real stability measure on bulk liquid, not packaging detail.
  • Assay and acid value reported on every COA. Our check on oxidative condition, not just the headline potency number.
  • Batch traceability to the producing plant. Full chain of custody documentation on request.
  • Export machinery handled in-house. Classification, labelling, freight booking and customs paperwork are ours to manage.
Packing & logistics

Packed the way your plant receives it

Liquid and solid forms need different packing logic entirely. Tell us your preferred form and production-line format and we will quote to it.

180 – 200 kg net

Lacquered steel drums (liquid)

The standard bulk-liquid format, under a nitrogen headspace to limit residual oxidation in transit and storage.

20 – 25 kg net

HDPE jerricans (liquid)

Smaller liquid-format containers suited to mid-size formulation lines that do not run full drums.

25 kg net

Fibre drums (powder/beadlet)

Lined fibre drums for the dry, diluted beadlet and powder forms used in tableting and feed premix lines.

500 g – 5 kg

Trial / sample quantities

Small packs in your chosen physical form, dispatched for formulation trials before a commercial order is placed.

FOB · CIF · CFR · DDP

Incoterms to suit you

Quoted on the Incoterm your purchasing team works to, with documentation filed before the booking is made.

Scheduled release

Contracted call-off supply

We hold contracted tonnage and release it against your production calendar, rather than asking you to warehouse it.

Safety, storage & handling

A vitamin ingredient with no significant GHS hazard classification

Vitamin E acetate carries no significant GHS hazard classification for its food, feed and cosmetic uses and is not regulated as a dangerous good. The guidance below is good-manufacturing-practice orientation — your facility's own food/pharma handling procedures and the SDS supplied with your consignment remain the governing documents.

Hazard classification

Vitamin E acetate is not classified as hazardous under GHS/CLP for its intended food, feed and cosmetic uses, and is not regulated as a dangerous good for any mode of transport. The main handling point is maintaining oxidative and physical quality — a lesser concern than for the free-tocopherol form, but not zero.

General handling notes

Treat it with the same care you would apply to any bulk oil-based or vitamin powder ingredient.

  • Minimise open-air exposure of the liquid. While more oxidation-resistant than free tocopherol, the ester still benefits from limited air contact in bulk handling.
  • Standard food/pharma PPE. Gloves during liquid transfer, plus a dust mask for the powder/beadlet form.
  • Clean up oil spills with absorbent material. No special chemical treatment is required — treat it as any other food-grade oil spill.
  • No special fire precautions beyond standard combustible-liquid practice. Check the SDS for the specific flash point of your batch form.

Storage

  • Cool, dry, dark warehouse storage. Reduces the slow residual oxidation that can still occur over long storage periods.
  • Keep containers tightly closed between uses. Nitrogen-blanket the headspace on opened bulk liquid drums where practical.
  • Avoid storage near strong oxidising agents. Standard good warehouse-segregation practice.
  • Rotate stock on a first-in-first-out basis. Straightforward inventory practice for any vitamin raw material with a defined shelf life.

Handling & PPE

  • Standard GMP handling. Treat it as you would any bulk oil-based vitamin ingredient in a food, feed, pharma or cosmetic facility.
  • Gloves during liquid transfer. Reasonable good practice to avoid oily residue rather than a hazard-driven requirement.
  • Dust mask for powder/beadlet handling. Standard good practice for any fine solid ingredient.
  • Food/cosmetic-contact-grade equipment where relevant. Standard requirement depending on your end use.

Transport

Vitamin E acetate is not regulated as a dangerous good for air, sea or road transport under IATA, IMDG or ADR/RID rules in its commercial forms. It ships as ordinary general cargo — ask us for a freight quote alongside your product pricing.

Quality & documentation

What travels with every consignment

On a vitamin that enters supplements, feed and cosmetic products in several physical forms, the paper trail is as important as the assay.

Certificate of Analysis

Batch-specific assay, acid value, refractive index or beadlet potency, heavy metals and microbiological results against your chosen monograph.

    Safety Data Sheet

    Full-section SDS covering composition, handling, storage and disposal, in the language your destination requires.

      Monograph compliance statement

      Written confirmation of compliance with the USP, EP or FCC monograph you have specified for your filing.

        Isomer / source declaration

        Written confirmation of DL- (synthetic) or D- (natural-source) form, supporting your own label and claims review.

          Certificate of Origin

          Chamber-attested where required, plus preferential-origin forms where a trade agreement gives your import duty relief.

            Retained & pre-shipment samples

            Pre-shipment samples carry the same COA as the commercial lot, so what your laboratory qualifies is exactly what arrives.

              The chemistry

              Why esterification is the whole point

              The chemistry of this molecule is really the chemistry of protecting a reactive antioxidant from itself. The outline below is general background, not a process disclosure.

              Build or isolate tocopherol

              Synthetic DL-alpha-tocopherol is built from trimethylhydroquinone and isophytol, or natural tocopherol is isolated from vegetable oil sources.

              Esterify the hydroxyl group

              The reactive phenolic hydroxyl on the tocopherol ring is reacted with acetic anhydride to form the acetate ester.

              Purify to specification

              The ester is purified and adjusted to the target physical form — liquid, powder or beadlet — under controlled conditions.

              QC release

              The batch is tested against the specified monograph for assay, acid value and physical properties before release.

              Why the ester, not the free vitamin

              The hydroxyl group that makes tocopherol such an effective antioxidant in the body is exactly what makes it unstable as a stored raw material:

              • Free tocopherol self-oxidises on exposure to air, light and heat, degrading potency during processing and storage.
              • The acetate ester blocks that reactive site, giving a shelf-stable commercial raw material.
              • Esterases cleave the ester back to active tocopherol after absorption, so the body receives the same biologically active vitamin.
              • Beadlet and powder forms exist purely for format — diluting the liquid onto a solid carrier for tableting, not changing the underlying chemistry.

              That stability trade-off is also why documentation matters here — confirming assay and acid value on the COA tells you the ester is intact and the batch has not partially hydrolysed in transit.

              Related vitamin intermediates
              MaterialPosition in the family
              Vitamin E acetate
              CAS 7695-91-2 — this product
              Fat-soluble antioxidant vitamin
              Niacinamide
              CAS 98-92-0
              Vitamin B3
              Calcium pantothenate
              CAS 137-08-6
              Vitamin B5
              Folic acid
              CAS 59-30-3
              Vitamin B9

              We supply across this vitamin and nutraceutical range — see the full intermediate range. Send the CAS number and we will confirm the correct material before quoting.

              Buying guidance

              What actually moves the price of this product

              Knowing what drives the quote helps you time a purchase and read whether an offer is realistic.

              Isophytol & trimethylhydroquinone feedstock

              Synthetic production depends on these specialty petrochemical intermediates, so their cost cycles filter through over a quarter.

              • We flag feedstock-driven moves in the quote
              • Longer contracts smooth short-term swings
              • Ask about indexed pricing on large volumes

              Synthetic (DL-) versus natural-source (D-)

              Natural-source material commands a meaningful premium over synthetic DL- for the same nominal potency, driven by "natural" label claims.

              • Confirm which claim your label actually needs
              • We quote both and let you compare
              • Over-specification is the commonest cost leak

              Physical form

              Beadlet and powder forms carry a formulation and dilution cost over the base liquid, reflecting the extra processing step.

              • Specify only the form your line actually needs
              • Liquid is the lowest-cost base form
              • We quote across all three forms for comparison

              Freight and packing format

              Non-dangerous-goods status keeps freight simple, though liquid drums cost more per kilo to move than bulk powder at scale.

              • Compare on landed cost, not ex-works
              • Ask about form-specific freight economics
              • We quote FOB, CIF, CFR or DDP as you prefer

              Source geography

              Global production is concentrated among a handful of large-scale vitamin manufacturers, so logistics lead time can matter as much as unit price.

              • We hold a second qualified source on this line
              • Ask which sourcing region best fits your lane
              • Regional stock can shorten lead time materially

              Shelf life and inventory

              A 24-month shelf life gives reasonable flexibility to buy ahead of a forecast price move, provided cool, dark storage is maintained.

              • Buy to schedule rather than to price alone
              • We hold inventory and release on call-off
              • Ask about scheduled despatch
              Grade selection at a glance
              If your end use is…Specify
              Softgel supplementsLiquid, USP/EP grade
              Tablets / dry-blend supplementsBeadlet form (dry dilution)
              Animal feed premixFeed-grade powder
              Cosmetic / personal-care activesLiquid, cosmetic-ingredient grade
              "Natural Vitamin E" label claimD-alpha-tocopheryl acetate (separate spec)

              Not sure which row you are in? Describe your formulation and our technical desk will recommend the physical form and grade.

              Technical support & compliance

              Support that goes beyond shipping the drum

              What our technical desk will do

              • Confirm physical form before anything else. Liquid, powder or beadlet drive completely different packing, freight and shelf-life profiles.
              • Confirm DL- versus D- requirement. Driven by your label claim, not just by cost, and we will say plainly which applies.
              • Recommend packing for your climate and transit. Nitrogen-headspace liquid packing is worth the cost on some routes and unnecessary on others.
              • Be straight about oxidative condition. Acid value tells a real story about batch handling — we will flag it if a batch looks marginal.

              Regulatory & compliance notes

              • Food and feed additive status varies by country. We check destination rules before quoting, not after you have raised the PO.
              • Cosmetic ingredient listings differ between regions. We supply the identity data you need for your cosmetic-ingredient filing (INCI, CAS, EC number).
              • Natural-source claims carry their own substantiation requirements. We pass through the producer's sourcing documentation to support your own claims review.
              • Pharmacopoeia compliance is batch-specific. We confirm which monograph version a given batch was tested against.

              None of the above is legal, nutritional or regulatory advice — your own regulatory affairs team owns the final compliance position for your product. What we commit to is accurate product identity data, an honest statement of specification, and complete documentation to work from.

              How to order

              From enquiry to delivered pallet

              Send the specification

              Product name or CAS 7695-91-2, DL- or D- form, physical form (liquid/powder/beadlet), end use, quantity, pack preference and destination port.

              Receive a firm quote

              Pricing, lead time, packing and Incoterm confirmed in writing within 24 hours — our sourcing desk is staffed around the clock.

              Qualify and approve

              Sample dispatched if you are qualifying a new source. Batch COA shared for your approval before the material is released.

              Ship and track

              Documentation issued, freight booked, and the consignment tracked through transit and clearance to your door.

              Common questions

              What buyers ask us about Vitamin E Acetate

              Why the acetate form rather than Vitamin E itself?
              Free alpha-tocopherol oxidises readily on exposure to air, light and heat, which limits its shelf life as a raw material. Esterifying it to the acetate protects the molecule from oxidation during processing and storage; the ester is then cleaved back to active tocopherol after absorption in the body.
              What is Vitamin E acetate used for?
              Principally as a stable source of Vitamin E in dietary supplements and multivitamin formulations, animal feed and premix manufacture, and cosmetic skin-care and hair-care formulations, where it functions as both an antioxidant and a skin-conditioning ingredient.
              What grade and physical form do you supply?
              We supply USP/EP/FCC-grade liquid DL-alpha-tocopheryl acetate as well as powder and beadlet (dry, diluted) forms for tableting and feed premix use. Tell us your formulation format and we will quote the matching grade.
              Is Vitamin E acetate hazardous to handle?
              No significant hazard classification applies under GHS/CLP for its intended food, feed and cosmetic uses, and it is not regulated as a dangerous good for transport. Standard good-manufacturing-practice handling for an oily nutraceutical ingredient still applies.
              How is the liquid form packed and what is the shelf life?
              The liquid is typically packed in lacquered steel drums or HDPE containers under nitrogen headspace to limit residual oxidation; beadlet and powder forms are packed in lined fibre drums or bags. Shelf life is typically 24 months stored sealed, cool and away from light.
              What is the minimum order quantity?
              Commercial supply typically starts at one 25 kg or 180–200 kg drum depending on form. Sample quantities from 500 g to 1 kg are available for formulation trials, with the full COA supplied alongside.
              Do you manufacture this yourself?
              No — Chelora Chemicals is a supplier and sourcing partner, not a manufacturer. We place your order with whichever qualified, audited producer fits your specification, form, volume and timeline, and hold a second source in reserve.

              Request pricing on Vitamin E Acetate

              Send your preferred physical form, DL- or D- requirement, intended end use, quantity, pack format and destination port. Our sourcing desk is available 24 hours a day, 7 days a week, and comes back with pricing, lead time and packing options.

              Email your enquirysource@cheloragroup.com
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